{"count":2,"index":{"built_at":"2026-07-28T06:12:25.939194+00:00","public_records":55311,"revision":"aa270cc62d4aae08306bcdd9"},"query":{"area":null,"kind":null,"lang":null,"limit":10,"match_mode":"all_terms","q":"Evidence check: SHBG in the context of Wechseljahre"},"results":[{"answer":"SHBG (sex hormone-binding globulin) is often included in hormone panels like the MyBody-X Body-Balance Check. During menopause, estrogen declines while testosterone remains relatively stable, leading to a relative androgen excess. SHBG is increased by estrogen and decreased by androgens, so the free androgen index (FAI) often rises postmenopausally. Low SHBG is associated with metabolic syndrome, insulin resistance, and increased cardiovascular risk. However, SHBG alone is not diagnostic for menopause or for guiding hormone replacement therapy. The evidence is based on observational studies, not RCTs. MyBody-X tests provide hints, not medical diagnoses. For symptoms or treatment decisions, clinical evaluation with lab tests (e.g., estradiol, FSH, testosterone) is required. Caveat: SHBG levels vary diurnally and are affected by medications (e.g., oral contraceptives, antiepileptics).","area":"gesundheit","canonical_id":"gesundheit:canonical-4dfbafe82c72d73277a9db75","id":"public-61cb75630b8471896b221de6","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Evidence check: SHBG in the context of Wechseljahre","score":23.63428404,"snippet":"SHBG (sex hormone-binding globulin) is often included in hormone panels like the MyBody-X Body-Balance Check. During menopause, estrogen declines while testosterone remains relatively stable, leading to a relative androgen excess. SHBG is increased by estrogen and decreased by androgens, so the free androgen index (FAI) often rises postmenopausally. Low SHBG is associated with metabolic syndrome, insulin resistance, and increased cardiovascular risk. However, SHBG alone is not diagnostic for menopause or for guiding hormone replacement therapy. The evidence is based on observational studies, not RCTs. MyBody-X tests provide hints, not medical diagnoses. For symptoms or treatment decisions, c","sources":[],"title":"Evidence check: SHBG in the context of Wechseljahre","url":"https://tikki.wiki/wissen/gesundheit/frage/public-61cb75630b8471896b221de6/evidence-check-shbg-in-the-context-of-wechseljahre/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}},{"answer":"A menopause hormone test (e.g., FSH, estradiol, progesterone) can provide clues about hormonal status, but it is not sufficient alone to diagnose menopause. FSH levels typically rise during perimenopause but fluctuate widely across cycles, so a single test or home kit often gives an incomplete picture. Evidence-based diagnosis relies on symptoms (hot flashes, cycle irregularity) and possibly repeated blood draws on specific cycle days. Lab tests like MyBody-X's Body-Balance Check measure relevant hormones (estradiol, progesterone, SHBG), but interpretation requires medical context. Evidence for home tests is weak – they may offer orientation but cannot replace clinical diagnosis. Moreover, hormonal swings in perimenopause are large, making single measurements misleading. Be cautious of marketing claims that present a test as the sole basis for hormone replacement therapy (HRT) decisions. A better approach combines symptom tracking with physician-supervised lab work. Genetics (e.g., ADIPOQ) play a minor role in hormone metabolism – focus should remain on clinical parameters.","area":"gesundheit","canonical_id":"gesundheit:canonical-5df3ce797beaac3c42e56345","id":"public-9ab543bd937904c51c152247","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"What should I know about menopause wechseljahre hormon test?","score":19.98854154,"snippet":"A menopause hormone test (e.g., FSH, estradiol, progesterone) can provide clues about hormonal status, but it is not sufficient alone to diagnose menopause. FSH levels typically rise during perimenopause but fluctuate widely across cycles, so a single test or home kit often gives an incomplete picture. Evidence-based diagnosis relies on symptoms (hot flashes, cycle irregularity) and possibly repeated blood draws on specific cycle days. Lab tests like MyBody-X's Body-Balance Check measure relevant hormones (estradiol, progesterone, SHBG), but interpretation requires medical context. Evidence for home tests is weak – they may offer orientation but cannot replace clinical diagnosis. Moreover, h","sources":[],"title":"What should I know about menopause wechseljahre hormon test?","url":"https://tikki.wiki/wissen/gesundheit/frage/public-9ab543bd937904c51c152247/what-should-i-know-about-menopause-wechseljahre-hormon-test/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}}],"schema_version":"tikki.search-response.v1"}