{"count":1,"index":{"built_at":"2026-07-27T12:57:51.000374+00:00","public_records":55311,"revision":"2683718554cb90ba1321a863"},"query":{"area":null,"kind":null,"lang":null,"limit":10,"match_mode":"all_terms","q":"Evidence check: SHBG in the context of Allergie"},"results":[{"answer":"The provided context does not contain direct evidence linking SHBG (sex hormone-binding globulin) to allergies. SHBG is primarily a carrier protein for sex hormones (testosterone, estradiol) and is studied in metabolic conditions, insulin resistance, and inflammatory markers like CRP and IL-6. The sources discuss allergy biomarkers such as IgE, IgG, CRP, IL-6, TNF, and explicitly reject IgG/IgG4 food tests per EAACI/AAAAI/DGAKI guidelines. No specific SHBG-allergy mechanism is mentioned. Therefore, the evidence is unclear. For a robust assessment, targeted studies on SHBG and allergic diseases (e.g., asthma, atopic dermatitis) would be required. Note: SHBG levels are influenced by hormones, liver function, and insulin – interpreting them in an allergy context remains speculative.","area":"gesundheit","canonical_id":"gesundheit:canonical-4cd1440a9bcf2f1f0574b58e","id":"public-55d68607c35fad41514d19d9","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Evidence check: SHBG in the context of Allergie","score":21.81745659,"snippet":"The provided context does not contain direct evidence linking SHBG (sex hormone-binding globulin) to allergies. SHBG is primarily a carrier protein for sex hormones (testosterone, estradiol) and is studied in metabolic conditions, insulin resistance, and inflammatory markers like CRP and IL-6. The sources discuss allergy biomarkers such as IgE, IgG, CRP, IL-6, TNF, and explicitly reject IgG/IgG4 food tests per EAACI/AAAAI/DGAKI guidelines. No specific SHBG-allergy mechanism is mentioned. Therefore, the evidence is unclear. For a robust assessment, targeted studies on SHBG and allergic diseases (e.g., asthma, atopic dermatitis) would be required. Note: SHBG levels are influenced by hormones, ","sources":[],"title":"Evidence check: SHBG in the context of Allergie","url":"https://tikki.wiki/wissen/gesundheit/frage/public-55d68607c35fad41514d19d9/evidence-check-shbg-in-the-context-of-allergie/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}}],"schema_version":"tikki.search-response.v1"}