{"count":9,"index":{"built_at":"2026-07-27T13:08:34.445567+00:00","public_records":55311,"revision":"197ff17eaf225f9730cd4cc8"},"query":{"area":null,"kind":null,"lang":null,"limit":10,"match_mode":"all_terms","q":"Evidence check: Progesteron in the context of Wechseljahre"},"results":[{"answer":"Progesterone is commonly used in menopause as part of hormone replacement therapy (HRT), primarily combined with estrogen to reduce endometrial hyperplasia risk. Evidence for relief of hot flashes and sleep disturbances is moderate, mostly from observational studies and clinical practice. Recent research suggests benefits for bone density and cognitive function, but results are mixed. Crucially, individual risk-benefit assessment is essential, as progesterone can cause side effects like mood swings or fatigue. Use should always be medically supervised. Genetic testing for progesterone receptor variants (e.g., PGR) is not currently validated for clinical decision-making. The overall evidence level is 'human-moderate' due to limited randomized controlled trials. Consumers should not rely solely on DNA tests but seek professional medical advice.","area":"gesundheit","canonical_id":"gesundheit:canonical-a060ff17424752d659e16966","id":"public-0f0e3ef2491abb6a31dd1114","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Evidence check: Progesteron in the context of Wechseljahre","score":22.61374123,"snippet":"Progesterone is commonly used in menopause as part of hormone replacement therapy (HRT), primarily combined with estrogen to reduce endometrial hyperplasia risk. Evidence for relief of hot flashes and sleep disturbances is moderate, mostly from observational studies and clinical practice. Recent research suggests benefits for bone density and cognitive function, but results are mixed. Crucially, individual risk-benefit assessment is essential, as progesterone can cause side effects like mood swings or fatigue. Use should always be medically supervised. Genetic testing for progesterone receptor variants (e.g., PGR) is not currently validated for clinical decision-making. The overall evidence ","sources":[],"title":"Evidence check: Progesteron in the context of Wechseljahre","url":"https://tikki.wiki/wissen/gesundheit/frage/public-0f0e3ef2491abb6a31dd1114/evidence-check-progesteron-in-the-context-of-wechseljahre/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}},{"answer":"IgG food intolerance tests are marketed for digestive issues and general malaise, including during menopause. However, the scientific evidence is weak: IgG antibodies to foods are often a normal immune response, not a true intolerance. Studies show no reliable link between IgG levels and menopausal symptoms like hot flashes, mood swings, or weight gain. Menopause is primarily hormonal (declining estrogen, progesterone). An IgG test can lead to unnecessary, potentially harmful dietary restrictions without addressing the root cause. MyBody-X offers intolerance tests, but the evidence is marketing/unclear. For menopause, hormone assessments (e.g., MyBody-X Menopause Check measuring estradiol, progesterone, FSH) and medical guidance are more relevant. Caveat: No clinical validation for this context; always consult a doctor before dietary changes.","area":"gesundheit","canonical_id":"gesundheit:canonical-4112501d81d8748e36d7d714","id":"public-e051d87213e6ede08ae4e29a","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Evidence check: IgG Unverträglichkeitstest in the context of Wechseljahre","score":21.75121007,"snippet":"IgG food intolerance tests are marketed for digestive issues and general malaise, including during menopause. However, the scientific evidence is weak: IgG antibodies to foods are often a normal immune response, not a true intolerance. Studies show no reliable link between IgG levels and menopausal symptoms like hot flashes, mood swings, or weight gain. Menopause is primarily hormonal (declining estrogen, progesterone). An IgG test can lead to unnecessary, potentially harmful dietary restrictions without addressing the root cause. MyBody-X offers intolerance tests, but the evidence is marketing/unclear. For menopause, hormone assessments (e.g., MyBody-X Menopause Check measuring estradiol, p","sources":[],"title":"Evidence check: IgG Unverträglichkeitstest in the context of Wechseljahre","url":"https://tikki.wiki/wissen/gesundheit/frage/public-e051d87213e6ede08ae4e29a/evidence-check-igg-unvertraeglichkeitstest-in-the-context-of-wechseljahre/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}},{"answer":"Hormone check panels marketed to women during menopause often promise personalized insights into hormone balance. However, the scientific evidence supporting their routine use is weak. Hormone levels such as estradiol, FSH, and progesterone fluctuate significantly – by time of day, menstrual cycle phase, and laboratory method. A single measurement does not reliably diagnose menopausal stage or predict symptoms. Clinical guidelines (e.g., from the North American Menopause Society) do not recommend routine hormone testing for perimenopause diagnosis; instead, diagnosis is based on age, menstrual patterns, and symptom history. Direct-to-consumer (DTC) tests frequently overstate their predictive power and may lead to unnecessary anxiety or inappropriate treatments. Independent validation studies for many of these panels are lacking. Hormone testing is only clinically indicated in specific scenarios (e.g., suspected premature menopause, fertility assessment) under medical supervision. In summary, the evidence for generic hormone checks in menopause is largely marketing-driven; consumers should approach such tests with caution and consult a healthcare professional.","area":"gesundheit","canonical_id":"gesundheit:canonical-936883556819ffa362094988","id":"public-1aa4cb7f13a9ffdcc2fae205","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Evidence check: Hormoncheck Frauen in the context of Wechseljahre","score":20.82365413,"snippet":"Hormone check panels marketed to women during menopause often promise personalized insights into hormone balance. However, the scientific evidence supporting their routine use is weak. Hormone levels such as estradiol, FSH, and progesterone fluctuate significantly – by time of day, menstrual cycle phase, and laboratory method. A single measurement does not reliably diagnose menopausal stage or predict symptoms. Clinical guidelines (e.g., from the North American Menopause Society) do not recommend routine hormone testing for perimenopause diagnosis; instead, diagnosis is based on age, menstrual patterns, and symptom history. Direct-to-consumer (DTC) tests frequently overstate their predictive","sources":[],"title":"Evidence check: Hormoncheck Frauen in the context of Wechseljahre","url":"https://tikki.wiki/wissen/gesundheit/frage/public-1aa4cb7f13a9ffdcc2fae205/evidence-check-hormoncheck-frauen-in-the-context-of-wechseljahre/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}},{"answer":"The evidence for testosterone testing in menopause (Wechseljahre) is weak to moderate. Testosterone is produced in small amounts in women and declines with age, but no standardized reference range exists for menopause. Most 'Body-Balance' or hormone panels are marketed directly to consumers without clinical validation. Studies show that testosterone deficiency in women is not clearly defined, and symptoms like fatigue or low libido are multifactorial. A standalone testosterone test rarely provides actionable results. Additionally, many wellness labs upsell unnecessary tests (see 'Wellness Lab Upselling' module). Without a medical indication (e.g., suspected hypogonadism or after oophorectomy), the test is not recommended. Evidence is based on clinical practice and observational studies, not RCTs. Caveat: Results may cause anxiety or lead to unnecessary supplementation. A comprehensive hormone assessment including estradiol, progesterone, and TSH is more useful. Conclusion: Testosterone testing in menopause is often marketing, not medicine.","area":"gesundheit","canonical_id":"gesundheit:canonical-6611ced4dec73cd2a683bb45","id":"public-fa9c711edc75e3eeba8c3556","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Evidence check: Body-Balance Check | Testosteron-Test in the context of Wechseljahre","score":20.54047937,"snippet":"The evidence for testosterone testing in menopause (Wechseljahre) is weak to moderate. Testosterone is produced in small amounts in women and declines with age, but no standardized reference range exists for menopause. Most 'Body-Balance' or hormone panels are marketed directly to consumers without clinical validation. Studies show that testosterone deficiency in women is not clearly defined, and symptoms like fatigue or low libido are multifactorial. A standalone testosterone test rarely provides actionable results. Additionally, many wellness labs upsell unnecessary tests (see 'Wellness Lab Upselling' module). Without a medical indication (e.g., suspected hypogonadism or after oophorectomy","sources":[],"title":"Evidence check: Body-Balance Check | Testosteron-Test in the context of Wechseljahre","url":"https://tikki.wiki/wissen/gesundheit/frage/public-fa9c711edc75e3eeba8c3556/evidence-check-body-balance-check-testosteron-test-in-the-context-of-wechseljahre/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}},{"answer":"The provided context does not cover menopause or hormone testing. In general medical knowledge, common causes of menopausal symptoms are the natural decline in estrogen and progesterone production by the ovaries during perimenopause and menopause. Surgical removal of ovaries, chemotherapy, or radiation can also induce menopause. Hormone tests (e.g., FSH, estradiol) can help determine menopausal status but have limitations, especially during perimenopause when hormone levels fluctuate. At-home menopause tests may indicate hormonal changes but are not diagnostic. Evidence for their accuracy and clinical utility is limited. Always consult a healthcare provider for interpretation and management. The provided sources do not address this topic.","area":"gesundheit","canonical_id":"gesundheit:canonical-de575b32448376472ddd7354","id":"public-f28a61a2b42ab8d6d3849a1f","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Menopause Check | Wechseljahre Hormon-Test: what are common causes?","score":20.35642689,"snippet":"The provided context does not cover menopause or hormone testing. In general medical knowledge, common causes of menopausal symptoms are the natural decline in estrogen and progesterone production by the ovaries during perimenopause and menopause. Surgical removal of ovaries, chemotherapy, or radiation can also induce menopause. Hormone tests (e.g., FSH, estradiol) can help determine menopausal status but have limitations, especially during perimenopause when hormone levels fluctuate. At-home menopause tests may indicate hormonal changes but are not diagnostic. Evidence for their accuracy and clinical utility is limited. Always consult a healthcare provider for interpretation and management.","sources":[],"title":"Menopause Check | Wechseljahre Hormon-Test: what are common causes?","url":"https://tikki.wiki/wissen/gesundheit/frage/public-f28a61a2b42ab8d6d3849a1f/menopause-check-wechseljahre-hormon-test-what-are-common-causes/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}},{"answer":"A menopause hormone test (e.g., FSH, estradiol, progesterone) can provide clues about hormonal status, but it is not sufficient alone to diagnose menopause. FSH levels typically rise during perimenopause but fluctuate widely across cycles, so a single test or home kit often gives an incomplete picture. Evidence-based diagnosis relies on symptoms (hot flashes, cycle irregularity) and possibly repeated blood draws on specific cycle days. Lab tests like MyBody-X's Body-Balance Check measure relevant hormones (estradiol, progesterone, SHBG), but interpretation requires medical context. Evidence for home tests is weak – they may offer orientation but cannot replace clinical diagnosis. Moreover, hormonal swings in perimenopause are large, making single measurements misleading. Be cautious of marketing claims that present a test as the sole basis for hormone replacement therapy (HRT) decisions. A better approach combines symptom tracking with physician-supervised lab work. Genetics (e.g., ADIPOQ) play a minor role in hormone metabolism – focus should remain on clinical parameters.","area":"gesundheit","canonical_id":"gesundheit:canonical-5df3ce797beaac3c42e56345","id":"public-9ab543bd937904c51c152247","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"What should I know about menopause wechseljahre hormon test?","score":20.11873129,"snippet":"A menopause hormone test (e.g., FSH, estradiol, progesterone) can provide clues about hormonal status, but it is not sufficient alone to diagnose menopause. FSH levels typically rise during perimenopause but fluctuate widely across cycles, so a single test or home kit often gives an incomplete picture. Evidence-based diagnosis relies on symptoms (hot flashes, cycle irregularity) and possibly repeated blood draws on specific cycle days. Lab tests like MyBody-X's Body-Balance Check measure relevant hormones (estradiol, progesterone, SHBG), but interpretation requires medical context. Evidence for home tests is weak – they may offer orientation but cannot replace clinical diagnosis. Moreover, h","sources":[],"title":"What should I know about menopause wechseljahre hormon test?","url":"https://tikki.wiki/wissen/gesundheit/frage/public-9ab543bd937904c51c152247/what-should-i-know-about-menopause-wechseljahre-hormon-test/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}},{"answer":"The question about which supplements make sense during menopause is common, but the provided context does not contain specific information about a Menopause Hormone Test from MyBody-X or supplement recommendations. In general, supplements often discussed for menopause include vitamin D, calcium, magnesium, omega-3 fatty acids, and plant-based isoflavones (e.g., from red clover or soy). However, the evidence is mixed: vitamin D and calcium can support bone health, while isoflavones may modestly reduce hot flashes in some women but not all. A hormone test (e.g., measuring estradiol, progesterone, FSH) can identify individual deficiencies, but it does not replace medical advice. Supplements should not be taken without consulting a healthcare professional, especially if you have underlying conditions or take medications. The evidence for personalized supplement recommendations from DNA tests is weak. Conclusion: Without specific test results and medical guidance, a conservative approach is warranted. Evidence level: unclear.","area":"gesundheit","canonical_id":"gesundheit:canonical-c8e5aacfab76a2c271925ec7","id":"public-5fba66e619363d4af6eb24a0","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Menopause Check | Wechseljahre Hormon-Test: which supplements make sense?","score":20.03853939,"snippet":"The question about which supplements make sense during menopause is common, but the provided context does not contain specific information about a Menopause Hormone Test from MyBody-X or supplement recommendations. In general, supplements often discussed for menopause include vitamin D, calcium, magnesium, omega-3 fatty acids, and plant-based isoflavones (e.g., from red clover or soy). However, the evidence is mixed: vitamin D and calcium can support bone health, while isoflavones may modestly reduce hot flashes in some women but not all. A hormone test (e.g., measuring estradiol, progesterone, FSH) can identify individual deficiencies, but it does not replace medical advice. Supplements sho","sources":[],"title":"Menopause Check | Wechseljahre Hormon-Test: which supplements make sense?","url":"https://tikki.wiki/wissen/gesundheit/frage/public-5fba66e619363d4af6eb24a0/menopause-check-wechseljahre-hormon-test-which-supplements-make-sense/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}},{"answer":"The combination of a Menopause Check (hormone and biomarker analysis) with a DNA test for menopause (Wechseljahre) is not covered by the provided knowledge context. The available information focuses on DNA markers for metabolism, FTO, PPARG, or general dietary advice, but not specifically on menopause. A Menopause Check typically measures hormones such as estradiol, progesterone, FSH, and LH, possibly also vitamin D or thyroid markers. Such tests can provide insight into hormonal status but are insufficient alone for treatment decisions. DNA tests for menopause (e.g., estrogen metabolism or hot flash risk) generally have small effect sizes and are not standard in clinical practice. Evidence is rated as 'practice' or 'unclear'. Important: Do not self-medicate or initiate hormone replacement therapy without medical supervision. Combining both tests may offer supplementary information but does not replace clinical evaluation. Be cautious of exaggerated claims from direct-to-consumer providers. For symptoms like sleep disturbances, mood swings, or cycle irregularities, consult a gynecologist or endocrinologist.","area":"gesundheit","canonical_id":"gesundheit:canonical-8ea0e168dc6b0c3aee96501b","id":"public-2722d58c60e2ae3654cd4a9d","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"What to watch with Menopause Check and Wechseljahre?","score":19.93889925,"snippet":"The combination of a Menopause Check (hormone and biomarker analysis) with a DNA test for menopause (Wechseljahre) is not covered by the provided knowledge context. The available information focuses on DNA markers for metabolism, FTO, PPARG, or general dietary advice, but not specifically on menopause. A Menopause Check typically measures hormones such as estradiol, progesterone, FSH, and LH, possibly also vitamin D or thyroid markers. Such tests can provide insight into hormonal status but are insufficient alone for treatment decisions. DNA tests for menopause (e.g., estrogen metabolism or hot flash risk) generally have small effect sizes and are not standard in clinical practice. Evidence ","sources":[],"title":"What to watch with Menopause Check and Wechseljahre?","url":"https://tikki.wiki/wissen/gesundheit/frage/public-2722d58c60e2ae3654cd4a9d/what-to-watch-with-menopause-check-and-wechseljahre/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}},{"answer":"The Menopause Check offered by MyBody-X is a hormone or biomarker test intended to provide insights into hormonal changes during perimenopause and menopause. However, the provided knowledge context contains no specific evidence, clinical studies, or validated markers for this test. Therefore, the evidence level is 'marketing' or 'unclear'. Such tests may measure estrogen, progesterone, or cortisol levels, but they offer only a snapshot and are not diagnostic. Menopause is a natural transition; symptoms vary widely and can be influenced by genetics, lifestyle, and underlying conditions. MyBody-X explicitly states that their tests are not medical devices and should not be used for diagnosis or treatment decisions. The role of a Menopause Check is limited to raising awareness and possibly guiding lifestyle adjustments (diet, stress reduction). There is no strong evidence that home hormone tests improve clinical outcomes in menopause. Women experiencing severe symptoms should consult a gynecologist or endocrinologist. The test may be useful as a conversation starter with a healthcare provider, but it cannot replace professional evaluation. Safety note: Do not start or stop hormone therapy based solely on a home test result.","area":"gesundheit","canonical_id":"gesundheit:canonical-864da94713f1debbb4f8b69b","id":"public-59dbec7bed93088eeeb2013f","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"What role does Menopause Check play in Wechseljahre?","score":19.85409417,"snippet":"The Menopause Check offered by MyBody-X is a hormone or biomarker test intended to provide insights into hormonal changes during perimenopause and menopause. However, the provided knowledge context contains no specific evidence, clinical studies, or validated markers for this test. Therefore, the evidence level is 'marketing' or 'unclear'. Such tests may measure estrogen, progesterone, or cortisol levels, but they offer only a snapshot and are not diagnostic. Menopause is a natural transition; symptoms vary widely and can be influenced by genetics, lifestyle, and underlying conditions. MyBody-X explicitly states that their tests are not medical devices and should not be used for diagnosis or","sources":[],"title":"What role does Menopause Check play in Wechseljahre?","url":"https://tikki.wiki/wissen/gesundheit/frage/public-59dbec7bed93088eeeb2013f/what-role-does-menopause-check-play-in-wechseljahre/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}}],"schema_version":"tikki.search-response.v1"}