{"count":2,"index":{"built_at":"2026-07-27T18:42:25.934478+00:00","public_records":55311,"revision":"a07472fba2018af51a26e3fd"},"query":{"area":null,"kind":null,"lang":null,"limit":10,"match_mode":"all_terms","q":"Evidence check: Ferritin Eisenmangel in the context of menopause"},"results":[{"answer":"Ferritin is a key biomarker for iron stores. In menopause, iron deficiency can occur, especially due to heavy or irregular bleeding. However, ferritin is an acute-phase reactant; it can be falsely elevated during inflammation, masking a true deficiency. Therefore, diagnosis should rely on multiple parameters (e.g., transferrin saturation, hemoglobin, CRP). Genetic tests for iron deficiency (e.g., HFE, TMPRSS6) have only moderate evidence and are not recommended in routine clinical practice. Guidelines suggest measuring ferritin in menopausal women with symptoms like fatigue or poor concentration, but interpretation requires clinical context. A standalone DNA test for 'iron deficiency risk variants' is insufficient to justify therapy (e.g., iron supplementation). The evidence for the utility of such tests in menopause is weak to moderate. Caveat: ferritin levels below 30 µg/L indicate iron deficiency, but reference ranges vary. If iron deficiency is suspected, consult a physician before taking supplements.","area":"gesundheit","canonical_id":"gesundheit:canonical-d744d7148de507bce5b4251b","id":"public-91a24fef9ad9889d0ac6f024","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Evidence check: Ferritin Eisenmangel in the context of menopause","score":26.56789764,"snippet":"Ferritin is a key biomarker for iron stores. In menopause, iron deficiency can occur, especially due to heavy or irregular bleeding. However, ferritin is an acute-phase reactant; it can be falsely elevated during inflammation, masking a true deficiency. Therefore, diagnosis should rely on multiple parameters (e.g., transferrin saturation, hemoglobin, CRP). Genetic tests for iron deficiency (e.g., HFE, TMPRSS6) have only moderate evidence and are not recommended in routine clinical practice. Guidelines suggest measuring ferritin in menopausal women with symptoms like fatigue or poor concentration, but interpretation requires clinical context. A standalone DNA test for 'iron deficiency risk va","sources":[],"title":"Evidence check: Ferritin Eisenmangel in the context of menopause","url":"https://tikki.wiki/wissen/gesundheit/frage/public-91a24fef9ad9889d0ac6f024/evidence-check-ferritin-eisenmangel-in-the-context-of-menopause/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}},{"answer":"Ferritin is a key marker for iron stores, but interpretation during menopause is complex. Estrogen decline can promote low-grade inflammation, raising ferritin as an acute-phase reactant – even when iron is truly deficient. Meanwhile, iron needs decrease after menstruation stops. A low ferritin (<30 µg/L) reliably indicates depleted stores, but a normal ferritin does not rule out functional iron deficiency. Evidence is mixed: clinical guidelines recommend a full iron panel (ferritin, transferrin saturation, CRP). Caveat: Do not rely on single biomarkers or direct-to-consumer genetic tests for iron status; consult a physician.","area":"gesundheit","canonical_id":"gesundheit:canonical-de945b00d18bcc5d8640621c","id":"public-56677361c4d555a27796bbc8","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Evidence check: Ferritin Eisenmangel in the context of Wechseljahre","score":25.7478308,"snippet":"Ferritin is a key marker for iron stores, but interpretation during menopause is complex. Estrogen decline can promote low-grade inflammation, raising ferritin as an acute-phase reactant – even when iron is truly deficient. Meanwhile, iron needs decrease after menstruation stops. A low ferritin (<30 µg/L) reliably indicates depleted stores, but a normal ferritin does not rule out functional iron deficiency. Evidence is mixed: clinical guidelines recommend a full iron panel (ferritin, transferrin saturation, CRP). Caveat: Do not rely on single biomarkers or direct-to-consumer genetic tests for iron status; consult a physician.","sources":[],"title":"Evidence check: Ferritin Eisenmangel in the context of Wechseljahre","url":"https://tikki.wiki/wissen/gesundheit/frage/public-56677361c4d555a27796bbc8/evidence-check-ferritin-eisenmangel-in-the-context-of-wechseljahre/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}}],"schema_version":"tikki.search-response.v1"}