{"count":2,"index":{"built_at":"2026-07-28T19:19:10.733897+00:00","public_records":70263,"revision":"4db6d26b3c449255bf596dd5"},"query":{"area":null,"kind":null,"lang":null,"limit":10,"match_mode":"all_terms","q":"Evidence check: CLOCK in the context of Sport"},"results":[{"answer":"The CLOCK gene is a core component of the circadian rhythm machinery. In sports, variants in CLOCK have been studied for their association with chronotype, optimal training timing, and injury risk. However, the evidence is moderate at best. While some GWAS and candidate gene studies report links to athletic performance (e.g., sprint or endurance), effect sizes are small and replication inconsistent. Lifestyle factors such as sleep hygiene, training schedule, and nutrition have a much larger impact. A direct-to-consumer DNA test for CLOCK variants alone cannot provide actionable training advice. It is not a substitute for assessing individual chronotype via validated questionnaires or actigraphy. The clinical utility remains unproven, and no specific supplementation or training modification is supported by current evidence. Caution: overinterpretation of such genetic results can lead to unnecessary changes in training routines.","answer_eligible":false,"area":"gesundheit","canonical_id":"gesundheit:canonical-c5f45c4b791a34c075de5c27","id":"public-2db7f33911662df495cc78c6","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Evidence check: CLOCK in the context of Sport","research_origin_label":"","score":25.47360497,"snippet":"The CLOCK gene is a core component of the circadian rhythm machinery. In sports, variants in CLOCK have been studied for their association with chronotype, optimal training timing, and injury risk. However, the evidence is moderate at best. While some GWAS and candidate gene studies report links to athletic performance (e.g., sprint or endurance), effect sizes are small and replication inconsistent. Lifestyle factors such as sleep hygiene, training schedule, and nutrition have a much larger impact. A direct-to-consumer DNA test for CLOCK variants alone cannot provide actionable training advice. It is not a substitute for assessing individual chronotype via validated questionnaires or actigra","source_count":0,"source_index_status":"pending","source_note":"Allgemeine Recherche; noch keine Quellen indexiert.","sources":[],"title":"Evidence check: CLOCK in the context of Sport","url":"https://tikki.wiki/wissen/gesundheit/frage/public-2db7f33911662df495cc78c6/evidence-check-clock-in-the-context-of-sport/","verification":{"answer_eligible":false,"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"research_origin_label":"","source_identity_verified":false,"source_index_status":"pending","source_note":"Allgemeine Recherche; noch keine Quellen indexiert.","tier":"existing_native_answer_privacy_screened_sources_pending"}},{"answer":"The provided context does not contain specific information about the CLOCK gene in relation to sports. CLOCK is a core circadian rhythm gene, and some research suggests variants may influence sleep patterns, recovery, and athletic performance. However, the evidence is mostly mechanistic or from observational studies, not yet actionable for individual athletes. Without direct data from the given sources, the usefulness of CLOCK testing for sports remains unclear. Athletes interested in circadian optimization should focus on sleep hygiene and timing of training/nutrition rather than relying solely on genetic results. The available snippets (lifestyle checklist, product pages, other gene FAQs) do not address CLOCK. Therefore, the evidence grade is 'unclear'.","answer_eligible":false,"area":"gesundheit","canonical_id":"gesundheit:canonical-ec5897f2b65c56b001a7098a","id":"public-85203f30f5fdd06b312115f3","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Is CLOCK useful for Sport?","research_origin_label":"","score":24.03730746,"snippet":"The provided context does not contain specific information about the CLOCK gene in relation to sports. CLOCK is a core circadian rhythm gene, and some research suggests variants may influence sleep patterns, recovery, and athletic performance. However, the evidence is mostly mechanistic or from observational studies, not yet actionable for individual athletes. Without direct data from the given sources, the usefulness of CLOCK testing for sports remains unclear. Athletes interested in circadian optimization should focus on sleep hygiene and timing of training/nutrition rather than relying solely on genetic results. The available snippets (lifestyle checklist, product pages, other gene FAQs) ","source_count":0,"source_index_status":"pending","source_note":"Allgemeine Recherche; noch keine Quellen indexiert.","sources":[],"title":"Is CLOCK useful for Sport?","url":"https://tikki.wiki/wissen/gesundheit/frage/public-85203f30f5fdd06b312115f3/is-clock-useful-for-sport/","verification":{"answer_eligible":false,"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"research_origin_label":"","source_identity_verified":false,"source_index_status":"pending","source_note":"Allgemeine Recherche; noch keine Quellen indexiert.","tier":"existing_native_answer_privacy_screened_sources_pending"}}],"schema_version":"tikki.search-response.v1"}