{"count":2,"index":{"built_at":"2026-07-27T12:04:40.942926+00:00","public_records":55311,"revision":"443fbdeedf251d1db1eba747"},"query":{"area":null,"kind":null,"lang":null,"limit":10,"match_mode":"all_terms","q":"Evidence check: CLOCK in the context of Haut"},"results":[{"answer":"The provided context does not contain direct evidence linking the CLOCK gene to skin health. CLOCK is a core circadian rhythm gene, and mechanistic research suggests the internal clock influences skin barrier function, collagen synthesis, and cell regeneration. However, the given sources (e.g., on MTHFR, ACE, LEPR, SIRT1) lack specific data on CLOCK and skin. Therefore, the evidence level is 'mechanistic' or 'unclear'. No direct clinical studies or genetic associations with skin aging or conditions are supported by the context. Consumer DNA tests that claim CLOCK variants affect skin are often based on weak or overhyped evidence. Without robust human studies, the utility of such analyses remains speculative. A healthy lifestyle including adequate sleep and UV protection is currently more important than single gene variants.","area":"gesundheit","canonical_id":"gesundheit:canonical-e0f695f21894e53ef896efd1","id":"public-5aa9bedb78d6d51eb7cb637c","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Evidence check: CLOCK in the context of Haut","score":21.76691615,"snippet":"The provided context does not contain direct evidence linking the CLOCK gene to skin health. CLOCK is a core circadian rhythm gene, and mechanistic research suggests the internal clock influences skin barrier function, collagen synthesis, and cell regeneration. However, the given sources (e.g., on MTHFR, ACE, LEPR, SIRT1) lack specific data on CLOCK and skin. Therefore, the evidence level is 'mechanistic' or 'unclear'. No direct clinical studies or genetic associations with skin aging or conditions are supported by the context. Consumer DNA tests that claim CLOCK variants affect skin are often based on weak or overhyped evidence. Without robust human studies, the utility of such analyses rem","sources":[],"title":"Evidence check: CLOCK in the context of Haut","url":"https://tikki.wiki/wissen/gesundheit/frage/public-5aa9bedb78d6d51eb7cb637c/evidence-check-clock-in-the-context-of-haut/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}},{"answer":"Based on the available context, there is no indication that MyBody-X offers a telomere length test or an epigenetic clock test for measuring biological age. The product descriptions and knowledge database do not list such analyses. Biological age determination is a complex field typically relying on epigenetic markers (e.g., DNA methylation) or telomere length measurements – neither of which appears in MyBody-X's current offerings. Simple DNA tests claiming to predict biological age are often not scientifically validated. If you want to measure your biological age, consider specialized laboratories or clinical providers using validated methods like the Horvath clock or telomere length assays. The evidence for this answer is graded as 'unclear' because product information may be incomplete, but currently no such tests are documented.","area":"gesundheit","canonical_id":"gesundheit:canonical-a79982da64e7b2fe778f9e5d","id":"public-a105f696393c2342c4cba208","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Evidence check: Vitamin D Test in the context of Haut","score":20.80476799,"snippet":"Based on the available context, there is no indication that MyBody-X offers a telomere length test or an epigenetic clock test for measuring biological age. The product descriptions and knowledge database do not list such analyses. Biological age determination is a complex field typically relying on epigenetic markers (e.g., DNA methylation) or telomere length measurements – neither of which appears in MyBody-X's current offerings. Simple DNA tests claiming to predict biological age are often not scientifically validated. If you want to measure your biological age, consider specialized laboratories or clinical providers using validated methods like the Horvath clock or telomere length assays","sources":[],"title":"Evidence check: Vitamin D Test in the context of Haut","url":"https://tikki.wiki/wissen/gesundheit/frage/public-a105f696393c2342c4cba208/evidence-check-vitamin-d-test-in-the-context-of-haut/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}}],"schema_version":"tikki.search-response.v1"}