{"count":1,"index":{"built_at":"2026-07-26T22:34:10.686833+00:00","public_records":55311,"revision":"03f31f12098967435e3a2fc7"},"query":{"area":null,"kind":null,"lang":null,"limit":10,"match_mode":"all_terms","q":"Common mistakes around TSH Genetik"},"results":[{"answer":"Common mistakes around TSH genetics: Many assume a DNA test can predict thyroid function. In reality, TSH-associated variants (e.g., in PDE8B, CAPZB) have small effects, explaining <5% of TSH variation. Commercial tests often exaggerate their predictive power. TSH levels fluctuate with time of day, diet, stress, and medications. A genetic finding does not replace clinical thyroid labs (TSH, fT3, fT4, antibodies). Also, 'risk variants' are often misinterpreted – many people with them have normal TSH. Evidence: human-moderate (GWAS, population studies). Caveat: No clinical recommendation exists for single variants.","area":"gesundheit","canonical_id":"gesundheit:canonical-35513785361ef41f41126da9","id":"public-c60850aa8489fd1ec550d0ac","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Common mistakes around TSH Genetik","score":40.78462553,"snippet":"Common mistakes around TSH genetics: Many assume a DNA test can predict thyroid function. In reality, TSH-associated variants (e.g., in PDE8B, CAPZB) have small effects, explaining <5% of TSH variation. Commercial tests often exaggerate their predictive power. TSH levels fluctuate with time of day, diet, stress, and medications. A genetic finding does not replace clinical thyroid labs (TSH, fT3, fT4, antibodies). Also, 'risk variants' are often misinterpreted – many people with them have normal TSH. Evidence: human-moderate (GWAS, population studies). Caveat: No clinical recommendation exists for single variants.","sources":[],"title":"Common mistakes around TSH Genetik","url":"https://tikki.wiki/wissen/gesundheit/frage/public-c60850aa8489fd1ec550d0ac/common-mistakes-around-tsh-genetik/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}}],"schema_version":"tikki.search-response.v1"}